Counting with Google.Me
Google search for "me" returns about 14,410,000,000 results. That's a lot of "me" content. About two hits for every human being on the planet Earth.
To compare with, Google search for site:me returns about 353,000,000 results. That's a lot of "me" content. About 1 for every American or European. Though, that's only 2.5% of "me" hits. There is pretty of the room for further growth.
To compare with, Google search for site:me "maine" returns about 17,400,000 results. That's about of 5% of .me pages indexed by Google. That's also about 5% of all "maine" hits on Google. Not bad for a small U.S. state with population of about 1.3 million people. That is 10 .me pages for every inhabitant of Maine.
To compare with, Google search for site:me "middle east" returns about 753,000 results. Would you think of .ME as Middle East? Now you can.
To compare with, Google search for site:me "motor engineer" returns only 323 results. One being motor-engineer.me. Just a park site and motorengineer.me still available.
To compare with, .RE, which is mainly known for hacks like foursqua.re, but as the possibilities are limited the zone is not so popular, could be used for real estate. However, Google search for site:re "real estate" returns only about 46,700 results. About 20 times less that .ME for Middle East.
Some numbers for a midday coffee thought.